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FOO LAB

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Impactful scientific discoveries through world-class research

Project RESET

Project RESET represents a distinct arm of the Foo Lab, with a team of clinicians and research coordinators leading NUS-CVRI and key local collaborators to support public health initiatives across Singapore to promote heart health awareness and begin to tackle the looming heart failure crisis in south east Asia. The project is aiming to recruit Singaporean patients with potential risk factors but no existing cardiac disease for enrollment.

5-year government-funded research initiative. It aims to gain a deeper understanding about the population’s metabolism, heart, and liver health as well as lifestyle behaviour to prevent heart diseases, including heart attack and stroke.

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  1. Dalakoti, M., & Foo, R. (2023). Redirecting immune, lipid, and metabolic drivers of early cardiovascular disease: the RESET cohort study and randomized trial. Eur Heart J, 44(39), 3939-3941. doi:10.1093/eurheartj/ehad543 (JIF: 35.85) 

  2. Dalakoti, M., Leow, M. K. S., Khoo, C. M., Yang, H., Ling, L. H., Muthiah, M., . . . Foo, R. (2023). Platform for the interdisciplinary study of cardiovascular, metabolic and neurovascular diseases (PICMAN) protocol. Sci Rep, 13(1). doi:10.1038/s41598-023-47407-y (JIF: 4.99)

  3. Yeo TM, Le TT, Bryant J, Lee V, Boubertakh R, Foo R, Wang W, Chin CWL. Prognostic Thresholds of Diffuse Myocardial Fibrosis on Cardiovascular Magnetic Resonance. Eur J Prev Cardiol. 2025 Feb 27:zwaf113. doi: 10.1093/eurjpc/zwaf113. Epub ahead of print. PMID: 40036633.

  4. Dalakoti M, Wong S, Lee W, Lee J, Yang H, Loong S, Loh PH, Tyebally S, Djohan A, Ong J, Yip J, Ngiam KY, Foo R. Incorporating AI into cardiovascular diseases prevention-insights from Singapore. Lancet Reg Health West Pac. 2024 May 27;48:101102. doi: 10.1016/j.lanwpc.2024.101102. PMID: 38855631; PMCID: PMC11154196.

  5. Dalakoti M, Foo R. Healthier SG - throwing down the gauntlet for specialists to integrate. Lancet Reg Health West Pac. 2023 Aug 14;37:100879. doi: 10.1016/j.lanwpc.2023.100879. PMID: 37636032; PMCID: PMC10457437.

  6. Dalakoti M, Lin NHY, Yap J, Cader A, Dipanker P, Lee D, Raja Shariff RE, Cuenza L, Honda S, Malis V, Jiang H, Hirachan A, Chimura M, Yeo TJ, Yeo KK, Tan JWC, Tromp J, Loh PH, Chew NWS, Wong S, Sia CH, Tan BYQ, Johar S, Lip GYH, Yang E, Virani SS, Hageman S, Liu H, Di Angelantonio E, Dorairaj P, Koh AS, Chin C, Al Mahmeed W, Chan MY, Foo R. Primary Prevention of Cardiovascular Disease in Asia: Challenges: A Narrative Review. JACC Adv. 2025 Mar 20;4(4):101670. doi: 10.1016/j.jacadv.2025.101670. Epub ahead of print. PMID: 40117691.

  7. Dalakoti M, Lin NHY, Yap J, Cader A, Dipanker P, Lee D, Raja Shariff RE, Cuenza L, Honda S, Malis V, Jiang H, Hirachan A, Chimura M, Yeo TJ, Yeo KK, Jack Wei Chieh T, Tromp J, Loh PH, Chew NWS, Wong S, Sia CH, Tan BYQ, Johar S, Lip GYH, Yang E, Virani SS, Hageman S, Liu H, Di Angelantonio E, Dorairaj P, Koh AS, Chin C, Al Mahmeed W, Chan MY, Foo R. Primary Prevention of Cardiovascular Disease in Asia: Opportunities and Solutions: A Narrative Review. JACC Adv. 2025 Mar 21;4(4):101676. doi: 10.1016/j.jacadv.2025.101676. Epub ahead of print. PMID: 40120215.

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