A New Approach to Heart Disease Prevention
Project RESET represents a distinct arm of the Foo Lab, with a team of clinicians and research coordinators leading NUS-CVRI and key local collaborators to support public health initiatives across Singapore to promote heart health awareness and begin to tackle the looming heart failure crisis in South East Asia.
The project is aiming to recruit Singaporean patients with potential risk factors but no existing cardiac disease for enrollment.
Another key interest is to understand genetic variation that influences disease risk and biology particularly in relation to South East Asia. We have mapped out the global cardiac enhancer–promoter landscape, and identified genetic variants that influence inter-individual variation through cis regulatory activity.
It is a 5-year government-funded research initiative. It aims to gain a deeper understanding about the population's metabolism, heart, and liver health as well as lifestyle behaviour to prevent heart diseases, including heart attack and stroke.
